Optically Mapping Multiple Bacterial Genomes Simultaneously in a Single Run

by Matthew C. Riley, James Eric Lee, Emil Lesho, Benjamin C. Kirkup

Optical mapping of bacterial chromosomes provides an unambiguous low-resolution sequence scaffold of the entire chromosome. In comparison to some techniques, such as pulse field gel electrophoresis, cost and throughput limit the application of this technique outside of genome finishing. We have demonstrated the production of multiple bacterial maps using a single set of consumables; this significantly reduces the time and expense of map production.

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Optically Mapping Multiple Bacterial Genomes Simultaneously in a Single Run
Syndicated from:PLoS ONE

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