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Dipotassium Glycyrrhizate Inhibits HMGB1-Dependent Inflammation and Ameliorates Colitis in Mice
by Roberta Vitali, Francesca Palone, Salvatore Cucchiara, Anna Negroni, Leonardo Cavone, Manuela Costanzo, Marina Aloi, Anna Dilillo, Laura Stronati Background High mobility group box-1 (HMGB1) is a DNA-binding protein that is released from injured cells during inflammation. Advances in targeting HMGB1 represent a major challenge to improve the treatment
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Oyster Shell Proteins Originate from Multiple Organs and Their Probable Transport Pathway to the Shell Formation Front
by Xiaotong Wang, Li Li, Yabing Zhu, Yishuai Du, Xiaorui Song, Yuanxin Chen, Ronglian Huang, Huayong Que, Xiaodong Fang, Guofan Zhang Mollusk shell is one kind of potential biomaterial, but its vague mineralization mechanism hinders its further application. Mollusk shell matrix proteins are
Differences in Body Fat Distribution Play a Role in the Lower Levels of Elevated Fasting Glucose amongst Ghanaian Migrant Women Compared to Men
by Mary Nicolaou, Anton E. Kunst, Wim B. Busschers, Irene G. van Valkengoed, Henriette Dijkshoorn, Linda Boateng, Lizzy M. Brewster, Marieke B. Snijder, Karien Stronks, Charles Agyemang Background Despite higher levels of obesity, West African migrant women appear to have lower rates of type 2 diabetes
Prediction of Soil Organic Carbon at the European Scale by Visible and Near InfraRed Reflectance Spectroscopy
by Antoine Stevens, Marco Nocita, Gergely Tóth, Luca Montanarella, Bas van Wesemael Soil organic carbon is a key soil property related to soil fertility, aggregate stability and the exchange of CO2 with the atmosphere. Existing soil maps and inventories can rarely be used to monitor the state and evolution
Billion-Pixel View of Mars Comes From Curiosity Rover
Source: JPL/NASA: Billion-Pixel View of Mars Comes From Curiosity Rover
Diet Shift and Its Impact on Foraging Behavior of Siberian Crane (Grus Leucogeranus) in Poyang Lake
by Yifei Jia, Shengwu Jiao, Yamian Zhang, Yan Zhou, Guangchun Lei, Guanhua Liu The study of habitat selection and diet has a long history in ecology. This is often used to assess the functional roles of wetland in biodiversity conservation. Shifting habitat and diet may be one of the survival strategies
A Phylogenomic Perspective on the Radiation of Ray-Finned Fishes Based upon Targeted Sequencing of Ultraconserved Elements (UCEs)
by Brant C. Faircloth, Laurie Sorenson, Francesco Santini, Michael E. Alfaro Ray-finned fishes constitute the dominant radiation of vertebrates with over 32,000 species. Although molecular phylogenetics has begun to disentangle major evolutionary relationships within this vast section of the Tree of
Application of Holistic Liquid Chromatography-High Resolution Mass Spectrometry Based Urinary Metabolomics for Prostate Cancer Detection and Biomarker Discovery
by Tong Zhang, David G. Watson, Lijie Wang, Muhammad Abbas, Laura Murdoch, Lisa Bashford, Imran Ahmad, Nga-Yee Lam, Anthony C. F. Ng, Hing Y. Leung Human exhibit wide variations in their metabolic profiles because of differences in genetic factors, diet and lifestyle. Therefore in order to detect metabolic
Genomic Porosity between Invasive Chondrostoma nasus and Endangered Endemic Parachondrostoma toxostoma (Cyprinidae): The Evolution of MHC IIB Genes
by Andrea Šimková, Kristína Civáňová, Lenka Gettová, André Gilles Two cyprinid species, Parachondrostoma toxostoma, an endemic threatened species, and Chondrostoma nasus, an invasive species, live in sympatry in southern France and form two sympatric zones where the presence of intergeneric
Celiac Disease–Specific TG2-Targeted Autoantibodies Inhibit Angiogenesis Ex Vivo and In Vivo in Mice by Interfering with Endothelial Cell Dynamics
by Suvi Kalliokoski, Ana-Marija Sulic, Ilma R. Korponay-Szabó, Zsuzsa Szondy, Rafael Frias, Mileidys Alea Perez, Stefania Martucciello, Anne Roivainen, Lauri J. Pelliniemi, Carla Esposito, Martin Griffin, Daniele Sblattero, Markku Mäki, Katri Kaukinen, Katri Lindfors, Sergio Caja A characteristic