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Traffic-Related Air Pollution and DNA Damage: A Longitudinal Study in Taiwanese Traffic Conductors
by Han-Bin Huang, Ching-Huang Lai, Guan-Wen Chen, Yong-Yang Lin, Jouni J. K. Jaakkola, Saou-Hsing Liou, Shu-Li Wang Background There is accumulating epidemiologic evidence that exposure to traffic-related air pollutants, including particulate matter (PM) and polyaromatic hydro carbons (PAHs), plays a role in etiology and prognosis of a large scale
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Conserved Orb6 Phosphorylation Sites Are Essential for Polarized Cell Growth in Schizosaccharomyces pombe
by Guohong Liu, Dallan Young The Ndr-related Orb6 kinase is a key regulator of polarized cell growth in fission yeast, however the mechanism of Orb6 activation is unclear. Activation of other Ndr kinases involves both autophosphorylation and phosphorylation by an upstream kinase. Previous
FADS1 FADS2 Gene Cluster, PUFA Intake and Blood Lipids in Children: Results from the GINIplus and LISAplus Studies
by Marie Standl, Eva Lattka, Barbara Stach, Sibylle Koletzko, Carl-Peter Bauer, Andrea von Berg, Dietrich Berdel, Ursula Krämer, Beate Schaaf, Stefan Röder, Olf Herbarth, Anette Buyken, Tim Drogies, Joachim Thiery, Berthold Koletzko, Joachim Heinrich, for the GINIplus Study Group¶, and LISAplus Study
Evaluation of Genetic Markers as Instruments for Mendelian Randomization Studies on Vitamin D
by Diane J. Berry, Karani S. Vimaleswaran, John C. Whittaker, Aroon D. Hingorani, Elina Hyppönen Background Mendelian randomization (MR) studies use genetic variants mimicking the influence of a modifiable exposure to assess and quantify a causal association with an outcome, with an aim to avoid problems
Improving Oral Hygiene Skills by Computer-Based Training: A Randomized Controlled Comparison of the Modified Bass and the Fones Techniques
by Daniela Harnacke, Simona Mitter, Marc Lehner, Jörn Munzert, Renate Deinzer Background Gingivitis and other plaque-associated diseases have a high prevalence in western communities even though the majority of adults report daily oral hygiene. This indicates a lack of oral hygiene skills. Currently,
Negative Priming Under Rapid Serial Visual Presentation
by Kin Fai Ellick Wong Negative priming (NP) was examined under a new paradigm wherein a target and distractors were temporally separated using rapid serial visual presentation (RSVP). The results from the two experiments revealed that (a) NP was robust under RSVP, such that the responses to
CCL18 in a Multiplex Urine-Based Assay for the Detection of Bladder Cancer
by Virginia Urquidi, Jeongsoon Kim, Myron Chang, Yunfeng Dai, Charles J. Rosser, Steve Goodison The early detection of bladder cancer (BCa) is pivotal for successful patient treatment and management. Through genomic and proteomic studies, we have identified a number of bladder cancer-associated
Modelling a Historic Oil-Tank Fire Allows an Estimation of the Sensitivity of the Infrared Receptors in Pyrophilous Melanophila Beetles
by Helmut Schmitz, Herbert Bousack Pyrophilous jewel beetles of the genus Melanophila approach forest fires and there is considerable evidence that these beetles can detect fires from great distances of more than 60 km. Because Melanophila beetles are equipped with infrared receptors and are
Increase of Carbapenem-Resistant Acinetobacter baumannii Infection in Acute Care Hospitals in Taiwan: Association with Hospital Antimicrobial Usage
by Chiu-Hsia Su, Jann-Tay Wang, Chao A. Hsiung, Li-Jung Chien, Cheng-Liang Chi, Hui-Tzu Yu, Feng-Yee Chang, Shan-Chwen Chang Objective Carbapenem-resistant Acinetobacter baumannii (CRAB) has emerged as an important pathogen causing healthcare-associated infections (HAIs) in Taiwan. The present study
Divergent Genomic and Epigenomic Landscapes of Lung Cancer Subtypes Underscore the Selection of Different Oncogenic Pathways during Tumor Development
by William W. Lockwood, Ian M. Wilson, Bradley P. Coe, Raj Chari, Larissa A. Pikor, Kelsie L. Thu, Luisa M. Solis, Maria I. Nunez, Carmen Behrens, John Yee, John English, Nevin Murray, Ming-Sound Tsao, John D. Minna, Adi F. Gazdar, Ignacio I. Wistuba, Calum E. MacAulay, Stephen Lam, Wan L. Lam