Section » Syndication
Zinc Transporter 8 and MAP3865c Homologous Epitopes are Recognized at T1D Onset in Sardinian Children
by Speranza Masala, Maria Antonietta Zedda, Davide Cossu, Carlo Ripoli, Mario Palermo, Leonardo A. Sechi Our group has recently demonstrated that Mycobacterium avium subspecies paratuberculosis (MAP) infection significantly associates with T1D in Sardinian adult patients. Due to the potential role played by MAP in T1D pathogenesis, it is relevant
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Characterization of Cell Wall Lipids from the Pathogenic Phase of Paracoccidioides brasiliensis Cultivated in the Presence or Absence of Human Plasma
by Larissa V. G. Longo, Ernesto S. Nakayasu, Felipe Gazos-Lopes, Milene C. Vallejo, Alisson L. Matsuo, Igor C. Almeida, Rosana Puccia Background The fungal cell wall is a complex and dynamic outer structure. In pathogenic fungi its components interact with the host, determining the infection fate. The
Emergent Dynamics from Spiking Neuron Networks through Symmetry Breaking of Connectivity
by M. Marmaduke Woodman, Viktor K. Jirsa Low-dimensional attractive manifolds with flows prescribing the evolution of state variables are commonly used to capture the lawful behavior of behavioral and cognitive variables. Neural network dynamics underlie many of the mechanistic explanations
What Autocorrelation Tells Us about Motor Variability: Insights from Dart Throwing
by Robert J. van Beers, Yor van der Meer, Richard M. Veerman In sports such as golf and darts it is important that one can produce ballistic movements of an object towards a goal location with as little variability as possible. A factor that influences this variability is the extent to which motor planning
Impact of Coronary Tortuosity on Coronary Blood Supply: A Patient-Specific Study
by Xinzhou Xie, Yuanyuan Wang, Hongmin Zhu, Hu Zhou, Jingmin Zhou Background Tortuous coronary arteries are commonly observed in clinical screenings and it may cause a reduction of the coronary pressure. However, whether this reduction leads to significant decreasing in the coronary blood supply is
Flexible Host Choice and Common Host Switches in the Evolution of Generalist and Specialist Cuckoo Bees (Anthophila: Sphecodes)
by Jana Habermannová, Petr Bogusch, Jakub Straka Specialization makes resource use more efficient and should therefore be a common process in animal evolution. However, this process is not as universal in nature as one might expect. Our study shows that Sphecodes (Halictidae) cuckoo bees frequently
Intact Olfaction in a Mouse Model of Multiple System Atrophy
by Florian Krismer, Gregor K. Wenning, Yuntao Li, Werner Poewe, Nadia Stefanova Background Increasing evidence suggests that olfaction is largely preserved in multiple system atrophy while most patients with Parkinson’s disease are hyposmic. Consistent with these observations, recent experimental
Cross-Brain Neurofeedback: Scientific Concept and Experimental Platform
by Lian Duan, Wei-Jie Liu, Rui-Na Dai, Rui Li, Chun-Ming Lu, Yu-Xia Huang, Chao-Zhe Zhu The present study described a new type of multi-person neurofeedback with the neural synchronization between two participants as the direct regulating target, termed as “cross-brain neurofeedback.” As a first
The Antimicrobial Compound Xantholysin Defines a New Group of Pseudomonas Cyclic Lipopeptides
by Wen Li, Hassan Rokni-Zadeh, Matthias De Vleeschouwer, Maarten G. K. Ghequire, Davy Sinnaeve, Guan-Lin Xie, Jef Rozenski, Annemieke Madder, José C. Martins, René De Mot The rhizosphere isolate Pseudomonas putida BW11M1 produces a mixture of cyclic lipopeptide congeners, designated xantholysins.
The Co-Repressor SMRT Delays DNA Damage-Induced Caspase Activation by Repressing Pro-Apoptotic Genes and Modulating the Dynamics of Checkpoint Kinase 2 Activation
by Claudio Scafoglio, Marcus Smolka, Huilin Zhou, Valentina Perissi, Michael G. Rosenfeld Checkpoint kinase 2 (Chk2) is a major regulator of DNA damage response and can induce alternative cellular responses: cell cycle arrest and DNA repair or programmed cell death. Here, we report the identification